LIZNE (Improve Tone, Texture, And Overall Skin Quality)

· Those in Tokyo seeking non-surgical ways to improve skin quality.
· Those with dry and dull skin.
· Those with aging skin.
· Those who want to reduce fine lines and wrinkles
· Those who wish to improve skin texture and radiance.

LIZNE is a regenerative skin treatment categorized as a skin booster, designed to improve overall quality and health of the skin through natural stimulation rather than artificial volume enhancement. Unlike dermal fillers that physically add volume or neuromodulators, for instance Botox that relax facial muscles, LIZNE focuses on encouraging the skin’s own regenerative processes. The key ingredient, Polynucleotide Sodium (PN), is a purified DNA compound extracted from salmon. This substance has been found to support cell activity, particularly the activity of fibroblasts, which are responsible for producing collagen and elastin. These structural proteins are essential for maintaining skin firmness, elasticity, and smooth texture.

The name “LIZNE” combines the words “LIZ” (a reference to vitality and youthfulness) and “Rene” (meaning rebirth), emphasizing the treatment’s purpose of reviving and renewing the skin. Rather than offering an instant but short-lived effect, LIZNE is formulated to enhance the skin’s natural ability to heal, hydrate, and restore itself over time. It is especially suitable for skin that appears dull, dry, or uneven in tone, and may be used to address issues such as fine lines, enlarged pores, acne scars, and mild pigmentation. LIZNE serves as a skin-conditioning therapy that strengthens and revitalizes the skin from within. By stimulating tissue regeneration and supporting moisture retention, the treatment gradually leads to improved skin texture, elasticity, and radiance.

The treatment is performed by Water Light Injection to infuse LIZNE into the deeper layers of skin. LIZNE functions by activating the skin's natural regenerative mechanisms. Its main component, Polynucleotide Sodium (PN), is a highly purified DNA fragment derived from salmon. Once introduced into the dermal layer, this compound stimulates fibroblasts, specialized skin cells that are responsible for producing collagen and elastin, which are essential for maintaining skin structure, elasticity, and resilience.

The polynucleotide molecules promote cellular repair, enhance hydration, and support tissue regeneration. Rather than creating immediate volume or altering muscle activity, LIZNE encourages gradual skin renewal. The polynucleotides remain stable within the tissue and decompose slowly, allowing sustained activity over time. This process helps improve skin density, refine texture, and restore a more even and luminous appearance. Because the formulation works in harmony with the skin’s biology, results develop progressively and appear natural.

1. Consultation will be conducted by the doctor.
2. The targeted area will be cleansed thoroughly to remove makeup, oils, and impurities.
3. LIZNE will be injected into the targeted area such as cheeks, forehead, or jawline using a fine needle.

<Advantages>
· Improves overall skin hydration
· Enhances skin elasticity
· Smooths fine lines and early wrinkles
· Refines skin texture
· Brightens dull or tired-looking face
· Minimizes appearance of pores
· Evens out skin tone

<Limitations>
· Temporary redness, swelling, or bruising may occur 1 to 3 days after the treatment
· Multiple sessions may be required to achieve the best results

· Avoid alcohol consumption and smoking 2 days before treatment
· Avoid taking blood-thinning medications 1 week before treatment
· Avoid any facial treatments at least 1 week before treatment
· Refrain from using harsh skincare products 3 to 5 days before treatment
· Inform doctor for any on-going medications or allergies

· Avoid touching, pressing, or massaging the treated area for at least 1 days after treatment
· Avoid applying makeup for 12 to 24 hours after treatment
· Avoid strenuous exercise, saunas, and hot baths 2 to 3 days after treatment
· Avoid harsh skincare products for 7 to 10 days after treatment

Q1: Is LIZNE painful?
A1: LIZNE is not painful; however, some patients may feel mild discomfort such as a warm or tingling sensation during the treatment.

Q2: Is LIZNE safe?
A2: LIZNE is typically safe as it contains high purified Polynucleotide Sodium derived from salmon DNA, which is biocompatible and considered very safe. As it is a natural substance, the risk of allergic reaction or adverse side effects is very low.

Q3: Can LIZNE help with acne scars and enlarged pores?
A3: Yes, one of the notable benefits of LIZNE is its ability to support skin regeneration, which helps in softening acne scars and reducing the appearance of large pores over time. Consistent treatment can lead to smoother, more even skin texture.

Q4: Is there any downtime after LIZNE?
A4: There is minimal downtime after LIZNE such as temporary redness, swelling, or bruising may occur 1 to 3 days after the treatment.

Q5: How long does the LIZNE procedure take?
A5: LIZNE procedure takes between 20 to 30 minutes.

[Clinic Name] Kojimachi Dermatology and Plastic Surgery Clinic
[Location] Tokyo, Japan
[Nearest Station/ Nearest Tourist Destination] Easily accessible from Kojimachi, Hanzomon, and Nagatacho Station within 1 to 5 minutes walking distance
[Clinic Opening Time] Monday - Saturday (10:00AM - 1:00PM, 2:00PM - 7:00PM); Closed on Sunday and public holiday

Trambellir is a health tourism platform and does not in any way provide, promote, or sell any medication or medical treatment to the Customers.
Customers are advised to contact the healthcare providers directly for any enquiries related to medical treatments.